4lim
Crystal structure of the catalytic subunit of yeast primaseCrystal structure of the catalytic subunit of yeast primase
Template:ABSTRACT PUBMED 24239947
FunctionFunction
[PRI1_YEAST] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. In a complex with DNA polymerase alpha (DNA polymerase alpha:primase) constitutes a replicative polymerase. Both primase components participate in formation of the active center, but the ATP-binding site is exclusively located on p48.
About this StructureAbout this Structure
4lim is a 1 chain structure. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Vaithiyalingam S, Arnett DR, Aggarwal A, Eichman BF, Fanning E, Chazin WJ. Insights into Eukaryotic Primer Synthesis from Structures of the p48 Subunit of Human DNA Primase. J Mol Biol. 2013 Nov 13. pii: S0022-2836(13)00718-3. doi:, 10.1016/j.jmb.2013.11.007. PMID:24239947 doi:http://dx.doi.org/10.1016/j.jmb.2013.11.007