Template:STRUCTURE 4mz2

Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domainCrystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain

DiseaseDisease

[SCN4B_HUMAN] Romano-Ward syndrome. The disease is caused by mutations affecting the gene represented in this entry.

FunctionFunction

[SCN4B_HUMAN] Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation (By similarity).

About this StructureAbout this Structure

4mz2 is a 1 chain structure. Full crystallographic information is available from OCA.

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OCA