Template:STRUCTURE 4mhc

Crystal Structure of a NucleoporinCrystal Structure of a Nucleoporin

Template:ABSTRACT PUBMED 24062435

FunctionFunction

[NU157_YEAST] Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.[1]

About this StructureAbout this Structure

4mhc is a 1 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Seo HS, Blus BJ, Jankovic NZ, Blobel G. Structure and nucleic acid binding activity of the nucleoporin Nup157. Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16450-16455. Epub 2013 Sep 23. PMID:24062435 doi:http://dx.doi.org/10.1073/pnas.1316607110
  1. Iouk T, Kerscher O, Scott RJ, Basrai MA, Wozniak RW. The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpoint. J Cell Biol. 2002 Dec 9;159(5):807-19. Epub 2002 Dec 9. PMID:12473689 doi:10.1083/jcb.200205068

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OCA