4kwv
Crystal Structure of human apo-QPRTCrystal Structure of human apo-QPRT
FunctionFunction
[NADC_HUMAN] Involved in the catabolism of quinolinic acid (QA).[1]
About this StructureAbout this Structure
4kwv is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Malik SS, Patterson DN, Ncube Z, Toth EA. The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid. Proteins. 2013 Aug 28. doi: 10.1002/prot.24406. PMID:24038671 doi:10.1002/prot.24406
- ↑ Liu H, Woznica K, Catton G, Crawford A, Botting N, Naismith JH. Structural and kinetic characterization of quinolinate phosphoribosyltransferase (hQPRTase) from homo sapiens. J Mol Biol. 2007 Oct 26;373(3):755-63. Epub 2007 Aug 24. PMID:17868694 doi:10.1016/j.jmb.2007.08.043