User:Alice Harmon/Sandbox 2
CDPK
Calcium-dependent protein kinases (CDPKs) are found in plants, algae, and apicomplexan protists, such as the parasites that cause malaria and toxoplasmosis. They are monomeric enzymes containing an amino-terminal protein kinase domain linked to a carboxy-terminal calcium-binding domain, that has sequence similarity to calmodulin. CDPKs belong to the calmodulin-dependent protein kinase family.
Crystal structures of inactive and active conformations of CDPK1 from Toxoplama gondii show the dramatic conformation change that occurs upon the binding of calcium to the regulatory domain [1].
The crystal structure 3hx4 of the shows
""References""