4fex
Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor tyrphostin AG1478Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor tyrphostin AG1478
About this StructureAbout this Structure
4fex is a 5 chain structure with sequence from Acinetobacter baumannii aye. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Stogios PJ, Spanogiannopoulos P, Evdokimova E, Egorova O, Shakya T, Todorovic N, Capretta A, Wright GD, Savchenko A. Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance. Biochem J. 2013 Jun 12. PMID:23758273 doi:10.1042/BJ20130317