4i2a
Binary complex of mouse TdT with ssDNA in absence of divalent transition metal ionBinary complex of mouse TdT with ssDNA in absence of divalent transition metal ion
FunctionFunction
[TDT_MOUSE] Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
About this StructureAbout this Structure
4i2a is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.