2wbe
Kinesin-5-Tubulin Complex with AMPPNPKinesin-5-Tubulin Complex with AMPPNP
Template:ABSTRACT PUBMED 19285086
FunctionFunction
[TBA1A_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [KL61_DROME] Important role in mitotic dividing cells. Microtubule motor required for spindle body separation. Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function. [TBB_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
About this StructureAbout this Structure
2wbe is a 3 chain structure with sequence from Bos taurus and Drosophila melanogaster. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Bodey AJ, Kikkawa M, Moores CA. 9-Angstrom structure of a microtubule-bound mitotic motor. J Mol Biol. 2009 May 1;388(2):218-24. Epub 2009 Mar 10. PMID:19285086 doi:10.1016/j.jmb.2009.03.008