3vms

Crystal structure of Staphylococcus aureus membrane-bound transglycosylase in complex with NBD-Lipid IICrystal structure of Staphylococcus aureus membrane-bound transglycosylase in complex with NBD-Lipid II

FunctionFunction

[MGT_STAAM] Involved in the biosynthesis of cell wall peptidoglycan. Responsible for the elongation of the glycan strands using lipid-linked disaccharide-pentapeptide as the substrate (By similarity).

About this StructureAbout this Structure

3vms is a 2 chain structure with sequence from Staphylococcus aureus subsp. aureus mu50. Full crystallographic information is available from OCA.

ReferenceReference

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↑ Huang CY, Shih HW, Lin LY, Tien YW, Cheng TJ, Cheng WC, Wong CH, Ma C. Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6496-501. Epub 2012 Apr 9. PMID:22493270 doi:10.1073/pnas.1203900109

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OCA

[1] Huang CY, Shih HW, Lin LY, Tien YW, Cheng TJ, Cheng WC, Wong CH, Ma C. Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6496-501. Epub 2012 Apr 9. PMID:22493270 doi:10.1073/pnas.1203900109

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