Circadian clock protein
Circadian clock proteins measure out the 24 hour circadian rhythm. In cyanobacteria protein KaiA stimulates KaiC which adds phosphate groups to itself. Then KaiC binds to KaiB which inactivates KaiA and causes the number of phosphate groups on KaiC to drop slowly. KaiB disconnects allowing KaiA to start the cycle again. For details of KaiC see Circadian Clock Protein KaiC.
3D Structures of circadian clock protein3D Structures of circadian clock protein
Updated on 11-July-2013
KaiAKaiA
1r5q – NoKaiA - Nostoc
1m2e, 1m2f – SeKaiA N terminal – Synechococcus elongatus - NMR
1q6a, 1q6b – SeKaiA C terminal - NMR
1v2z – SeKaiA C terminal
1r8j – SeKaiA
1suy, 1sv1 – SeKaiA C terminal + KaiC peptide - NMR
4g86 – SeKaiA + DBMIB
KaiBKaiB
1r5q – NoKaiB
1wwj – SyKaiB - Synechocystis
1vgl, 2qke – SeKaiB
KaiCKaiC
1tf7, 2gbl – SyKaiC
1u9i, 3dvl, 3jzm, 3k09, 3k0a, 3k0c, 3k0e, 3k0f, 3s1a, 4dug, 4ijm – SeKaiC (mutant)