Leukocyte immunoglobulin-like receptor

<StructureSection load='1p7q' size='350' side='right' caption='Structure of human leukocyte immunoglobulin-like receptor ligand-binding domain (yellow) complex with class I MHC (grey), β-2 microglobulin (green) and POL polyprotein peptide (pink) (PDB entry 1p7q)' scene=>

Leukocyte immunoglobulin-like receptors (LIR) or CD85 have extracellular immunoglobulin domains. LIR modulates a variety of immune cells. LIR interacts with class I MHC molecules.

3D structures of leukocyte immunoglobulin-like receptor3D structures of leukocyte immunoglobulin-like receptor

Updated on 04-July-2013

LIR-1

1g0x, 1ufu – hLIR ligand-binding domain – human
1ugn, 1vdg – hLIR ligand-binding domain (mutant)

LIR-1 complexes

1p7q – hLIR ligand-binding domain + class I MHC + β-2 microglobulin + POL polyprotein peptide
3d2u – hLIR ligand-binding domain + herpesvirus UL18 + β-2 microglobulin + actin peptide