3ubg

Crystal structure of Drosophila N-cadherin EC1-3, IICrystal structure of Drosophila N-cadherin EC1-3, II

FunctionFunction

[CADN_DROME] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May associate with arm neural isoform and participate in the transmission of developmental information.

About this StructureAbout this Structure

3ubg is a 2 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.

ReferenceReference

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↑ Jin X, Walker MA, Felsovalyi K, Vendome J, Bahna F, Mannepalli S, Cosmanescu F, Ahlsen G, Honig B, Shapiro L. Crystal structures of Drosophila N-cadherin ectodomain regions reveal a widely used class of Ca2+-free interdomain linkers. Proc Natl Acad Sci U S A. 2011 Dec 14. PMID:22171007 doi:10.1073/pnas.1117538108

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OCA

[1] Jin X, Walker MA, Felsovalyi K, Vendome J, Bahna F, Mannepalli S, Cosmanescu F, Ahlsen G, Honig B, Shapiro L. Crystal structures of Drosophila N-cadherin ectodomain regions reveal a widely used class of Ca2+-free interdomain linkers. Proc Natl Acad Sci U S A. 2011 Dec 14. PMID:22171007 doi:10.1073/pnas.1117538108

[xtra 1]