4br1
Protease-induced heterodimer of human triosephosphate isomerase.Protease-induced heterodimer of human triosephosphate isomerase.
DiseaseDisease
[TPIS_HUMAN] Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) [MIM:190450]. TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection.
About this StructureAbout this Structure
4br1 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Homo sapiens
- Triose-phosphate isomerase
- Castillo-Villanueva, A.
- DeLaMora-DeLaMora, I.
- Enriquez-Flores, S.
- Garcia-Torres, I.
- Gomez-Manzo, S.
- Hernandez-Alcantara, G.
- Lopez-Velazquez, G.
- Marcial-Quino, J.
- Mendez, S T.
- Mendoza-Hernandez, G.
- Oria-Hernandez, J.
- Reyes-Vivas, H.
- Torres-Arroyo, A.
- Torres-Larios, A.
- Hydrolase
- Protease degradation