4bqa

Crystal structure of the ETS domain of human ETS2 in complex with DNACrystal structure of the ETS domain of human ETS2 in complex with DNA

FunctionFunction

[ETS2_HUMAN] Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.^[1]

About this StructureAbout this Structure

4bqa is a 9 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

↑ Wasylyk C, Schlumberger SE, Criqui-Filipe P, Wasylyk B. Sp100 interacts with ETS-1 and stimulates its transcriptional activity. Mol Cell Biol. 2002 Apr;22(8):2687-702. PMID:11909962

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OCA

[1] Wasylyk C, Schlumberger SE, Criqui-Filipe P, Wasylyk B. Sp100 interacts with ETS-1 and stimulates its transcriptional activity. Mol Cell Biol. 2002 Apr;22(8):2687-702. PMID:11909962

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