Arsenate reductase

<StructureSection load='1j9b' size='350' side='right' caption='Structure of arsenate reductase complex with arsenate, thiarsahydroxy-cysteine and Cs+ ion (dark purple) (PDB entry 1j9b)' scene=>

Arsenate reductase (AsR) catalyzes the conversion of arsenate (As) and glutaredoxin to arsenite and glutaredoxin disulfide. AsR is part of the arsenic detoxification pathway.

3D structures of arsenate reducatse3D structures of arsenate reducatse

Updated on 16-May-2013

1jf8, 1ljl – SaAsR – Staphylococcus aureus
1jfv, 1lk0, 1rxi, 2cd7, 2fxi – SaAsR (mutant)
1jl3 – BsAsR – Bacillus subtilis
1z2d, 1z2e – BsAsR - NMR
1i9d – EcAsR – Escherichia coli
1s3c, 1s3d, 1sd8, 1sd9, 1sk2 – EcAsR (mutant)
2l17, 2l18 – SyAsR – Synechocystis - NMR
2l19 – SyAsR (mutant) - NMR

Arsenate reductase complexesArsenate reductase complexes

1jzw – EcAsR + arsonocysteine
1sk1 – EcAsR (mutant) + arsonocysteine
1sjz, 1sk0 – EcAsR (mutant) + arsonocysteine + AsO3
1j9b – EcAsR + AsO3 + thiarsahydroxy-cysteine
1lju – SaAsR (mutant) + arsonocysteine
1rxe – SaAsR (mutant) + mercapto-nitrobenzoate
2ipa – BsAsR (mutant) + thioredoxin (mutant)