2fdq
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crystal structure of ACBP from Armadillo Harderian Gland
OverviewOverview
The X-ray structure of the tetragonal form of apo acyl-CoA-binding protein (ACBP) from the Harderian gland of the South American armadillo Chaetophractus villosus has been solved. ACBP is a carrier for activated long-chain fatty acids and has been associated with many aspects of lipid metabolism. Its secondary structure is highly similar to that of the corresponding form of bovine ACBP and exhibits the unique flattened alpha-helical bundle (up-down-down-up) motif reported for animal, yeast and insect ACBPs. Conformational differences are located in loops and turns, although these structural differences do not suffice to account for features that could be related to the unusual biochemistry and lipid metabolism of the Harderian gland.
About this StructureAbout this Structure
2FDQ is a Single protein structure of sequence from Chaetophractus villosus. Full crystallographic information is available from OCA.
ReferenceReference
Structure of armadillo ACBP: a new member of the acyl-CoA-binding protein family., Costabel MD, Ermacora MR, Santome JA, Alzari PM, Guerin DM, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Oct 1;62(Pt, 10):958-61. Epub 2006 Sep 30. PMID:17012783
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