3npe

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Template:STRUCTURE 3npe

Structure of VP14 in complex with oxygenStructure of VP14 in complex with oxygen

Template:ABSTRACT PUBMED 20884803

FunctionFunction

[NCED1_MAIZE] Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity. Catalyzes the first step of abscisic-acid biosynthesis from carotenoids. Not active on the all-trans isomers of violaxanthin and neoxanthin. Contributes probably to abscisic acid synthesis for the induction of seed dormancy.[1] [2] [3]

About this StructureAbout this Structure

3npe is a 1 chain structure with sequence from Zea mays. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Messing SA, Gabelli SB, Echeverria I, Vogel JT, Guan JC, Tan BC, Klee HJ, McCarty DR, Amzel LM. Structural insights into maize viviparous14, a key enzyme in the biosynthesis of the phytohormone abscisic acid. Plant Cell. 2010 Sep;22(9):2970-80. Epub 2010 Sep 30. PMID:20884803 doi:10.1105/tpc.110.074815
  1. Tan BC, Schwartz SH, Zeevaart JA, McCarty DR. Genetic control of abscisic acid biosynthesis in maize. Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):12235-40. PMID:9342392
  2. Schwartz SH, Tan BC, Gage DA, Zeevaart JA, McCarty DR. Specific oxidative cleavage of carotenoids by VP14 of maize. Science. 1997 Jun 20;276(5320):1872-4. PMID:9188535
  3. Messing SA, Gabelli SB, Echeverria I, Vogel JT, Guan JC, Tan BC, Klee HJ, McCarty DR, Amzel LM. Structural insights into maize viviparous14, a key enzyme in the biosynthesis of the phytohormone abscisic acid. Plant Cell. 2010 Sep;22(9):2970-80. Epub 2010 Sep 30. PMID:20884803 doi:10.1105/tpc.110.074815

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