3o4r
Crystal Structure of Human Dehydrogenase/Reductase (SDR family) member 4 (DHRS4)Crystal Structure of Human Dehydrogenase/Reductase (SDR family) member 4 (DHRS4)
FunctionFunction
[DHRS4_HUMAN] Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones (By similarity).
About this StructureAbout this Structure
3o4r is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.