4i03
Human MMP12 in complex with a PEG-linked bifunctional L-glutamate motif inhibitorHuman MMP12 in complex with a PEG-linked bifunctional L-glutamate motif inhibitor
FunctionFunction
[MMP12_HUMAN] May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
About this StructureAbout this Structure
4i03 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.