User:Michael Roberts/BIOL115 Chymo

Chymotrypsin.

Chymotrypsin is a member of a family of enzymes all of which cleave peptide bonds through the action of an active site serine (the serine proteases). This family includes the pancreatic enzymes chymotrypsin, trypsin and elastase as well as a variety of other proteases (e.g. cocoonase, thrombin, acrosomal protease, etc.). Chymotrypsin, trypsin and elastase show a high degree of similarity in their overall tertiary structure, but have different substrate specificities determined by the different properties of the substrate binding site on each enzyme.

Click on the 'green links' in the text in the scrollable section below to examine this molecule in more detail.

<StructureSection load='1afq' size='500' side='right' caption='Structure of Chymotrypsin (PDB entry 1afq)' scene='User:Michael_Roberts/BIOL115_Chymo/Start/1'>