2wr6
STRUCTURE OF THE COMPLEX OF RBP4 WITH LINOLEIC ACIDSTRUCTURE OF THE COMPLEX OF RBP4 WITH LINOLEIC ACID
DiseaseDisease
[RET4_HUMAN] Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.
FunctionFunction
[RET4_HUMAN] Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.
About this StructureAbout this Structure
2wr6 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.