3idp
B-Raf V600E kinase domain in complex with an aminoisoquinoline inhibitorB-Raf V600E kinase domain in complex with an aminoisoquinoline inhibitor
About this StructureAbout this Structure
3idp is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Smith AL, Demorin FF, Paras NA, Huang Q, Petkus JK, Doherty EM, Nixey T, Kim JL, Whittington DA, Epstein LF, Lee MR, Rose MJ, Babij C, Fernando M, Hess K, Le Q, Beltran P, Carnahan J. Selective Inhibitors of the Mutant B-Raf Pathway: Discovery of a Potent and Orally Bioavailable Aminoisoquinoline. J Med Chem. 2009 Sep 18. PMID:19764794 doi:10.1021/jm901081g