1svm

Ligands:

, ,

Related:

Structural annotation:
Resources:	CATH : 1Svma03, 1Svma01, 1Svmb01, 1Svmb03, 1Svmc01, 1Svmc03, 1Svmd01, 1Svmd03, 1Svme01, 1Svme03, 1Svmf01, 1Svmf03 InterPro : Ipr014015, Ipr010932, Ipr003133, Ipr001623 Pfam : PF06431 UniProt : P03070

Functional annotation:
Cellular component:	nucleus
Biological process:	DNA replication
Molecular function:	ATP binding heat shock protein binding metal ion binding nucleotide binding zinc ion binding DNA binding DNA replication origin binding protein binding

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

About this StructureAbout this Structure

1svm is a 6 chain structure with sequence from Simian virus 40. The August 2006 RCSB PDB Molecule of the Month feature on AAA+ Proteases by David S. Goodsell is 10.2210/rcsb_pdb/mom_2006_8. Full crystallographic information is available from OCA.

↑ Gai D, Zhao R, Li D, Finkielstein CV, Chen XS. Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen. Cell. 2004 Oct 1;119(1):47-60. PMID:15454080 doi:10.1016/j.cell.2004.09.017
↑ Lilyestrom W, Klein MG, Zhang R, Joachimiak A, Chen XS. Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor. Genes Dev. 2006 Sep 1;20(17):2373-82. PMID:16951253 doi:http://dx.doi.org/20/17/2373
↑ Steere AN, Byrne SL, Chasteen ND, Smith VC, Macgillivray RT, Mason AB. Evidence that His349 acts as a pH-inducible switch to accelerate receptor-mediated iron release from the C-lobe of human transferrin. J Biol Inorg Chem. 2010 Aug 14. PMID:20711621 doi:10.1007/s00775-010-0694-2 20711621 10.1007/s00775-010-0694-2