Fasciculin

File:1fas.png

Crystal Structure of Fasciculin 1fas

Fasciculins (FAS) are toxins produced by the snake green mamba. FAS1 and FAS2 are known to bind to acetylcholinesterase (AChE) and cause severe fasciculations. The images at the left and at the right correspond to one representative FAS, i.e. the crystal structure of Fasciculin 1 (1fas). For toxins in Proteopedia see Toxins.

3D Structures of Fasciculin3D Structures of Fasciculin

Update January 2013

FasciculinFasciculin

1fas – FAS1
1fsc - FAS2

FAS+ AChEFAS+ AChE

2x8b, 1b41, 4ey8 – FAS2+hAChE – human
1f8u - FAS2+hAChE (mutant)
1ku6, 1mah - FAS2+mAChE – mouse
1fss - FAS2+AChE – Torpedo californica