1w39

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File:1w39.gif


1w39, resolution 3.75Å

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CRYSTAL STRUCTURE OF AN ARTIFICIAL TOP COMPONENT OF TURNIP YELLOW MOSAIC VIRUS

OverviewOverview

Empty capsids (artificial top component) of turnip yellow mosaic virus were co-crystallized with an encapsidation initiator RNA hairpin. No clear density was observed for the RNA, but there were clear differences in the conformation of a loop of the coat protein at the opening of the pentameric capsomer (formed by five A-subunits) protruding from the capsid, compared to the corresponding loop in the intact virus. Further differences were found at the N terminus of the A-subunit. These differences have implications for the mechanism of decapsidation of the virus, required for infection.

About this StructureAbout this Structure

1W39 is a Single protein structure of sequence from Turnip yellow mosaic virus. Full crystallographic information is available from OCA.

ReferenceReference

Crystal structure of an empty capsid of turnip yellow mosaic virus., van Roon AM, Bink HH, Plaisier JR, Pleij CW, Abrahams JP, Pannu NS, J Mol Biol. 2004 Aug 27;341(5):1205-14. PMID:15321716

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