Template:STRUCTURE 2ffl

File:2ffl.png

Crystal Structure of Dicer from Giardia intestinalisCrystal Structure of Dicer from Giardia intestinalis

Template:ABSTRACT PUBMED 16410517

About this StructureAbout this Structure

2ffl is a 4 chain structure with sequence from Giardia intestinalis. The February 2008 RCSB PDB Molecule of the Month feature on Small Interfering RNA by David S. Goodsell is 10.2210/rcsb_pdb/mom_2008_2. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1][xtra 2]

  1. Macrae IJ, Zhou K, Li F, Repic A, Brooks AN, Cande WZ, Adams PD, Doudna JA. Structural basis for double-stranded RNA processing by Dicer. Science. 2006 Jan 13;311(5758):195-8. PMID:16410517 doi:311/5758/195
  2. Laskowski RA, Thornton JM. Understanding the molecular machinery of genetics through 3D structures. Nat Rev Genet. 2008 Feb;9(2):141-51. PMID:18160966 doi:10.1038/nrg2273

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