2c6e
AURORA A KINASE ACTIVATED MUTANT (T287D) IN COMPLEX WITH A 5-AMINOPYRIMIDINYL QUINAZOLINE INHIBITORAURORA A KINASE ACTIVATED MUTANT (T287D) IN COMPLEX WITH A 5-AMINOPYRIMIDINYL QUINAZOLINE INHIBITOR
Template:ABSTRACT PUBMED 16337122
About this StructureAbout this Structure
2c6e is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Heron NM, Anderson M, Blowers DP, Breed J, Eden JM, Green S, Hill GB, Johnson T, Jung FH, McMiken HH, Mortlock AA, Pannifer AD, Pauptit RA, Pink J, Roberts NJ, Rowsell S. SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1320-3. Epub 2005 Dec 5. PMID:16337122 doi:10.1016/j.bmcl.2005.11.053
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OCACategories:
- Pages with broken file links
- Homo sapiens
- Non-specific serine/threonine protein kinase
- Anderson, M.
- Breed, J.
- Mcmiken, H H.J.
- Pannifer, A D.
- Pauptit, R A.
- Rowsell, S.
- Atp-binding
- Aurora
- Cancer
- Cell cycle
- Kinase
- Nucleotide- binding
- Phosphorylation
- Serine/threonine-protein kinase
- Transferase
- Transferase-inhibitor complex
- Transferase/inhibitor