1z8g
Crystal structure of the extracellular region of the transmembrane serine protease hepsin with covalently bound preferred substrate.Crystal structure of the extracellular region of the transmembrane serine protease hepsin with covalently bound preferred substrate.
About this StructureAbout this Structure
1z8g is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Herter S, Piper DE, Aaron W, Gabriele T, Cutler G, Cao P, Bhatt AS, Choe Y, Craik CS, Walker N, Meininger D, Hoey T, Austin RJ. Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers. Biochem J. 2005 Aug 15;390(Pt 1):125-36. PMID:15839837 doi:10.1042/BJ20041955