1u1s
|
Hfq protein from Pseudomonas aeruginosa. Low-salt crystals
OverviewOverview
The structure of the Hfq protein from Pseudomonas aeruginosa was determined using two different ionic conditions. In both cases the molecules formed identical hexameric rings, but some variations in the crystal packing were revealed. Hfq belongs to the family of Sm/LSm proteins, the members of which can form hexameric as well as heptameric rings. Comparative analysis of known structures of this protein family shows that the fragment of the Sm-fold responsible for oligomerization is strongly structurally conserved. In the heptameric ring, three conserved hydrogen bonds between beta-strands of adjacent molecules hold together the monomers, whereas in the hexameric rings of Hfq an additional conserved inaccessible hydrogen bond between neighbouring monomers is observed.
About this StructureAbout this Structure
1U1S is a Single protein structure of sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.
ReferenceReference
Structure of Pseudomonas aeruginosa Hfq protein., Nikulin A, Stolboushkina E, Perederina A, Vassilieva I, Blaesi U, Moll I, Kachalova G, Yokoyama S, Vassylyev D, Garber M, Nikonov S, Acta Crystallogr D Biol Crystallogr. 2005 Feb;61(Pt 2):141-6. Epub 2005, Jan 19. PMID:15681864
Page seeded by OCA on Thu Feb 21 15:19:53 2008
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCA- Pages with broken file links
- Pseudomonas aeruginosa
- Single protein
- Blaesi, U.
- Garber, M.
- Kachalova, G.
- Moll, I.
- Nikonov, S V.
- Nikulin, A D.
- Perederina, I.
- RSGI, RIKEN Structural Genomics/Proteomics Initiative.
- Stolboushkina, E A.
- Vassilieva, I M.
- Vassylyev, D.
- Yokoyama, S.
- Hf1
- Hfq
- Riken structural genomics/proteomics initiative
- Rsgi
- Sm-like bacterial protein
- Structural genomics