4dmx
Cathepsin K inhibitorCathepsin K inhibitor
Template:ABSTRACT PUBMED 22742641
About this StructureAbout this Structure
4dmx is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Dossetter A, Beeley H, Bowyer J, Cook CR, Crawford JJ, Finlayson JE, Heron NM, Heyes C, Highton AJ, Hudson JA, Jestel A, Kenny PW, Krapp S, Martin S, Macfaul PA, McGuire TM, Morentin-Gutierrez P, Morley AD, Morris JJ, Page KM, Rosenbrier-Ribeiro L, Sawney H, Steinbacher S, Smith C, Vickers M. (1R,2R)-N-(1-cyanocyclopropyl)-2-(6-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indole -2-carbonyl)cyclohexanecarboxamide (AZD4996): A potent and highly selective Cathepsin K inhibitor for the treatment of osteoarthritis. J Med Chem. 2012 Jun 28. PMID:22742641 doi:10.1021/jm3007257
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OCACategories:
- Pages with broken file links
- Cathepsin K
- Homo sapiens
- Beeley, H.
- Bowyer, J.
- Cook, C R.
- Crawford, J J.
- Dossetter, A G.
- Finlayson, J E.
- Gutierrez, P M.
- Heron, N M.
- Heyes, C.
- Highton, A J.
- Hudson, J A.
- Jestel, A.
- Kenny, P W
- Krapp, S.
- MacFaul, P A.
- Martin, S.
- McGuire, T M.
- Morley, A D.
- Morris, J J.
- Page, K M.
- Ribeiro, L Rosenbrier.
- Sawney, H.
- Smith, C.
- Steinbacher, S.
- Vickers, M.
- Cathepsin k inhibitor
- Hydrolase-hydrolase inhibitor complex
- Osteoarthritis