Glycogen synthase kinase 3

From Proteopedia
Revision as of 15:18, 1 January 2013 by Michal Harel (talk | contribs) (New page: {{STRUCTURE_4dit| PDB=4dit | SIZE=400| SCENE= |right|CAPTION=Human glycogen synthase 3 β complex with inhibitor, 4dit }} '''Glycogen synthase kinase 3''' (GSK-3) is a serine/threon...)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search

Template:STRUCTURE 4dit

Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase. GSK-3 is active in a number of intracellular signaling pathways. GSK-3 regulates glycogen synthase as well as other proteins. GSK-3 inhibition is studied as a therapeutic target in diseases like Alzheimer, diabetes, bipolar disorder and some cancers.

3D structures of glycogen synthase kinase 33D structures of glycogen synthase kinase 3

1i09, 1h8f – hGSK-3 β – human
1gng - hGSK-3 β + Frattide peptide
1o9u - hGSK-3 β + Axin peptide
1q4l, 1uv5, 1q5k, 1r0e, 2o5k, 2ow3, 3du8, 3f7z, 3f88, 3i4b, 3gb2, 3l1s, 3q3b, 3zrk, 3zrl, 3zrm, 3sd0, 4dit, 4afj, 4acc, 4acd, 4acg, 4ach, 3say - hGSK-3 β + inhibitor
1pyx, 1j1b - hGSK-3 β + AMPPNP
1j1c - hGSK-3 β + ADP
1q3d, 1q3w, 1q41 - hGSK-3 β + ATP-mimetic inhibitor
2jld - hGSK-3 β + Ru complex + peptide
3m1s, 3pup - hGSK-3 β + Ru complex
3zdi - hGSK-3 β + Axin peptide + inhibitor

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=Glycogen_synthase_kinase_3&oldid=1640594"