Template:STRUCTURE 2ydw

File:2ydw.png

Crystal Structure of the First Bromodomain of Human Brd2 with the inhibitor GW841819XCrystal Structure of the First Bromodomain of Human Brd2 with the inhibitor GW841819X

Template:ABSTRACT PUBMED 21568322

About this StructureAbout this Structure

2ydw is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Chung CW, Coste H, White JH, Mirguet O, Wilde J, Gosmini RL, Delves C, Magny SM, Woodward R, Hughes SA, Boursier EV, Flynn H, Bouillot AM, Bamborough P, Brusq JM, Gellibert FJ, Jones EJ, Riou AM, Homes P, Martin SL, Uings IJ, Toum J, Clement CA, Boullay AB, Grimley RL, Blandel FM, Prinjha RK, Lee K, Kirilovsky J, Nicodeme E. Discovery and Characterization of Small Molecule Inhibitors of the BET Family Bromodomains. J Med Chem. 2011 Jun 9;54(11):3827-3838. Epub 2011 May 13. PMID:21568322 doi:10.1021/jm200108t

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