Plexin

Plexin (PLX) is the receptor for semaphorin.

3D structures of plexin3D structures of plexin

Updated June 2012

Plexin APlexin A

3al8, 3oky – mPLX-A2 + semaphorin-6A – mouse

3al9, 3okt – mPLX-A2 extracellular domain
3ig3 - mPLX-A3 intracellular domain
3ryt - mPLX-A1 intracellular domain + Ras-related C3 botulinum toxin substrate
3q3j - hPLX-A2 binding domain + Rho-related GTP-binding protein Rho6 – human
4e74 - hPLX-A4 Rho GTPase-binding domain

Plexin BPlexin B

2r2o – hPLX-B1 effector domain

2rex - hPLX-B1 effector domain + Rho-related GTP-binding protein Rho6

2jph - hPLX-B1 Rho GTPase-binding domain – NMR
4e71 - hPLX-B2 Rho GTPase-binding domain
3ol2 - hPLX-B1 + semaphorin 4D

3sua, 3su8 – hPLX-B1 + RAS-related C3 botulinum toxin substrate

3hm6 - hPLX-B1 cytoplasmic domain + peptide

Plexin CPlexin C

3kuz - hPLX-C1 ubiquitin-like domain

3nvn, 3nvq – hPLX-C1 + semaphorin 7A

Plexin DPlexin D

3h6n - hPLX-D1 ubiquitin-like domain