RA Mediated T-reg Differentiation
IntroductionIntroduction
T-regulatory cells (T-regs) are a small subset of CD4+ T-cells that exhibit strong down regulation of immune system activity in their local environment. They are distinguished from other CD4+ T-cells by the expression of FOXP3, a gene regulator.
| Ligand Binding DomainRARα-RXRα HeterodimerRARα-RXRα Ligand Interactions |
DNA Binding DomainRXRα-DNA InteractionsDR-5 Specificity |
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