Colicin I receptor

  Template:STRUCTURE 2hdi

Colicin I receptor (Cir) is an E. coli outer membrane protein which binds colicin Ia. Upon binding it changes its conformation enabling the colicin to insert into the inner membrane forming a voltage-dependent ion channel resulting in killing the bacteria.

3D Structures of Colicin I receptor3D Structures of Colicin I receptor

2hdf – EcCir – Escherichia coli
2hdi – EcCir + colicin Ia receptor-binding domain