2i0h

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File:2i0h.png

Template:STRUCTURE 2i0h

The structure of p38alpha in complex with an arylpyridazinoneThe structure of p38alpha in complex with an arylpyridazinone

Template:ABSTRACT PUBMED 16945533

About this StructureAbout this Structure

2i0h is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1][xtra 2]

  1. Natarajan SR, Heller ST, Nam K, Singh SB, Scapin G, Patel S, Thompson JE, Fitzgerald CE, O'Keefe SJ. p38 MAP kinase inhibitors. Part 6: 2-arylpyridazin-3-ones as templates for inhibitor design. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5809-13. Epub 2006 Aug 30. PMID:16945533 doi:10.1016/j.bmcl.2006.08.074
  2. Lahiri SD, Zhang G, Dunaway-Mariano D, Allen KN. Diversification of function in the haloacid dehalogenase enzyme superfamily: The role of the cap domain in hydrolytic phosphoruscarbon bond cleavage. Bioorg Chem. 2006 Dec;34(6):394-409. Epub 2006 Oct 27. PMID:17070898 doi:10.1016/j.bioorg.2006.09.007

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