2fz8

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File:2fz8.png

Template:STRUCTURE 2fz8

Human Aldose reductase complexed with inhibitor zopolrestat at 1.48 A(1 day soaking).Human Aldose reductase complexed with inhibitor zopolrestat at 1.48 A(1 day soaking).

Template:ABSTRACT PUBMED 16952371

About this StructureAbout this Structure

2fz8 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Steuber H, Zentgraf M, Gerlach C, Sotriffer CA, Heine A, Klebe G. Expect the unexpected or caveat for drug designers: multiple structure determinations using aldose reductase crystals treated under varying soaking and co-crystallisation conditions. J Mol Biol. 2006 Oct 13;363(1):174-87. Epub 2006 Aug 9. PMID:16952371 doi:http://dx.doi.org/10.1016/j.jmb.2006.08.011

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