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3os3

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Template:STRUCTURE 3os3

File:3os3.png

Mitogen-activated protein kinase kinase 1 (MEK1) in complex with CH4858061 and MgATPMitogen-activated protein kinase kinase 1 (MEK1) in complex with CH4858061 and MgATP

Template:ABSTRACT PUBMED 21316218

About this StructureAbout this Structure

3os3 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Isshiki Y, Kohchi Y, Iikura H, Matsubara Y, Asoh K, Murata T, Kohchi M, Mizuguchi E, Tsujii S, Hattori K, Miura T, Yoshimura Y, Aida S, Miwa M, Saitoh R, Murao N, Okabe H, Belunis C, Janson C, Lukacs C, Schuck V, Shimma N. Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent. Bioorg Med Chem Lett. 2011 Jan 21. PMID:21316218 doi:10.1016/j.bmcl.2011.01.062

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