3cwj
Crystal structure of hcv ns5b polymerase with a novel pyridazinone inhibitorCrystal structure of hcv ns5b polymerase with a novel pyridazinone inhibitor
About this StructureAbout this Structure
3cwj is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Ellis DA, Blazel JK, Webber SE, Tran CV, Dragovich PS, Sun Z, Ruebsam F, McGuire HM, Xiang AX, Zhao J, Li LS, Zhou Y, Han Q, Kissinger CR, Showalter RE, Lardy M, Shah AM, Tsan M, Patel R, LeBrun LA, Kamran R, Bartkowski DM, Nolan TG, Norris DA, Sergeeva MV, Kirkovsky L. 4-(1,1-Dioxo-1,4-dihydro-1lambda6-benzo[1,4]thiazin-3-yl)-5-hydroxy-2H-pyr idazin-3-ones as potent inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4628-32. Epub 2008 Jul 10. PMID:18662878 doi:10.1016/j.bmcl.2008.07.014