1mu6
Crystal Structure of Thrombin in Complex with L-378,622Crystal Structure of Thrombin in Complex with L-378,622
Template:ABSTRACT PUBMED 12570369
About this StructureAbout this Structure
1mu6 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Burgey CS, Robinson KA, Lyle TA, Sanderson PE, Lewis SD, Lucas BJ, Krueger JA, Singh R, Miller-Stein C, White RB, Wong B, Lyle EA, Williams PD, Coburn CA, Dorsey BD, Barrow JC, Stranieri MT, Holahan MA, Sitko GR, Cook JJ, McMasters DR, McDonough CM, Sanders WM, Wallace AA, Clayton FC, Bohn D, Leonard YM, Detwiler TJ Jr, Lynch JJ Jr, Yan Y, Chen Z, Kuo L, Gardell SJ, Shafer JA, Vacca JP. Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines. J Med Chem. 2003 Feb 13;46(4):461-73. PMID:12570369 doi:http://dx.doi.org/10.1021/jm020311f
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OCACategories:
- Pages with broken file links
- Homo sapiens
- Thrombin
- Barrow, J C.
- Bohn, D.
- Burgey, C S.
- Chen, Z.
- Clayton, F C.
- Coburn, C A.
- Cook, J J.
- Detwiler, T J.
- Dorsey, B D.
- Gardell, S J.
- Holahan, M A.
- Krueger, J A.
- Kuo, L.
- Leonard, Y M.
- Lewis, S D.
- Lucas, B J.
- Lyle, E A.
- Lyle, T A.
- Lynch, J J.
- McDonough, C M.
- McMasters, D R.
- Miller-Stein, C.
- Robinson, K A.
- Sanders, W M.
- Sanderson, P E.
- Shafer, J A.
- Singh, R.
- Sitko, G R.
- Stranieri, M T.
- Vacca, J P.J.
- Wallace, A A.
- White, R B.
- Williams, P D.
- Wong, B.
- Yan, Y.
- Blood clotting
- Hydrolase
- Hydrolase-blood clotting complex
- Hydrolase-hydrolase inhibitor complex
- Hydrolase-inhibitor complex