3jwq
Crystal structure of chimeric PDE5/PDE6 catalytic domain complexed with sildenafilCrystal structure of chimeric PDE5/PDE6 catalytic domain complexed with sildenafil
About this StructureAbout this Structure
3jwq is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Barren B, Gakhar L, Muradov H, Boyd KK, Ramaswamy S, Artemyev NO. Structural basis of phosphodiesterase 6 inhibition by the C-terminal region of the gamma-subunit. EMBO J. 2009 Nov 18;28(22):3613-22. Epub 2009 Oct 1. PMID:19798052 doi:10.1038/emboj.2009.284
- ↑ Goc A, Chami M, Lodowski DT, Bosshart P, Moiseenkova-Bell V, Baehr W, Engel A, Palczewski K. Structural characterization of the rod cGMP phosphodiesterase 6. J Mol Biol. 2010 Aug 20;401(3):363-73. Epub 2010 Jul 1. PMID:20600113 doi:10.1016/j.jmb.2010.06.044