2w3k
CRYSTAL STRUCTURE OF FXA IN COMPLEX WITH 4,4-DISUBSTITUTED PYRROLIDINE-1,2-DICARBOXAMIDE INHIBITOR 1CRYSTAL STRUCTURE OF FXA IN COMPLEX WITH 4,4-DISUBSTITUTED PYRROLIDINE-1,2-DICARBOXAMIDE INHIBITOR 1
Template:ABSTRACT PUBMED 19231206
About this StructureAbout this Structure
2w3k is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Van Huis CA, Casimiro-Garcia A, Bigge CF, Cody WL, Dudley DA, Filipski KJ, Heemstra RJ, Kohrt JT, Leadley RJ Jr, Narasimhan LS, McClanahan T, Mochalkin I, Pamment M, Peterson JT, Sahasrabudhe V, Schaum RP, Edmunds JJ. Exploration of 4,4-disubstituted pyrrolidine-1,2-dicarboxamides as potent, orally active Factor Xa inhibitors with extended duration of action. Bioorg Med Chem. 2009 Mar 15;17(6):2501-11. Epub 2009 Feb 3. PMID:19231206 doi:10.1016/j.bmc.2009.01.063
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OCACategories:
- Pages with broken file links
- Coagulation factor Xa
- Homo sapiens
- Casimiro-Garcia, A.
- Huis, C A.Van.
- Mochalkin, I.
- Zhang, E.
- Blood clotting
- Blood coagulation
- Cleavage on pair of basic residue
- Drug design
- Egf-like domain
- Fxa coagulation factor inhibitor
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Hydroxylation
- Protease
- Secreted
- Serine protease
- Zymogen