1pq2
Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8
Template:ABSTRACT PUBMED 14676196
About this StructureAbout this Structure
1pq2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Schoch GA, Yano JK, Wester MR, Griffin KJ, Stout CD, Johnson EF. Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site. J Biol Chem. 2004 Mar 5;279(10):9497-503. Epub 2003 Dec 15. PMID:14676196 doi:10.1074/jbc.M312516200
- ↑ Yano JK, Hsu MH, Griffin KJ, Stout CD, Johnson EF. Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen. Nat Struct Mol Biol. 2005 Sep;12(9):822-3. Epub 2005 Aug 7. PMID:16086027 doi:http://dx.doi.org/10.1038/nsmb971
- ↑ Wu ZL, Podust LM, Guengerich FP. Expansion of substrate specificity of cytochrome P450 2A6 by random and site-directed mutagenesis. J Biol Chem. 2005 Dec 9;280(49):41090-100. Epub 2005 Oct 7. PMID:16215230 doi:10.1074/jbc.M508182200