Template:STRUCTURE 3bsa

File:3bsa.png

Crystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone InhibitorCrystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone Inhibitor

Template:ABSTRACT PUBMED 18242088

About this StructureAbout this Structure

3bsa is a 2 chain structure with sequence from Viruses. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Zhou Y, Webber SE, Murphy DE, Li LS, Dragovich PS, Tran CV, Sun Z, Ruebsam F, Shah AM, Tsan M, Showalter RE, Patel R, Li B, Zhao Q, Han Q, Hermann T, Kissinger CR, Lebrun L, Sergeeva MV, Kirkovsky L. Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5- hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1413-8. Epub 2008 Jan 8. PMID:18242088 doi:S0960-894X(08)00010-3

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