2eb3
Crystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNPCrystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNP
Template:ABSTRACT PUBMED 22349823
About this StructureAbout this Structure
2eb3 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Yoshikawa S, Kukimoto-Niino M, Parker L, Handa N, Terada T, Fujimoto T, Terazawa Y, Wakiyama M, Sato M, Sano S, Kobayashi T, Tanaka T, Chen L, Liu ZJ, Wang BC, Shirouzu M, Kawa S, Semba K, Yamamoto T, Yokoyama S. Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor. Oncogene. 2012 Feb 20. doi: 10.1038/onc.2012.21. PMID:22349823 doi:10.1038/onc.2012.21
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OCACategories:
- Pages with broken file links
- Homo sapiens
- Receptor protein-tyrosine kinase
- Kukimoto-Niino, M.
- RSGI, RIKEN Structural Genomics/Proteomics Initiative.
- Senba, K.
- Shirouzu, M.
- Yamamoto, T.
- Yokoyama, S.
- Yoshikawa, S.
- Atp-binding
- Cell cycle
- Disease mutation
- Ec 2 7.10 1
- Kinase
- National project on protein structural and functional analyse
- Nppsfa
- Phosphorylation
- Receptor
- Riken structural genomics/proteomics initiative
- Rsgi
- Structural genomic
- Transferase
- Transmembrane
- Tyrosine-protein kinase