Cruzain

Cruzain (Cru) is the major cysteine protease present in Trypanosoma cruzi which is the parasite causing Chagas disease. 3D structures of cruzain 1aim, 2aim, 1me3, 1me4 – Cru catalytic domain + methylketone inhibitor – Trypanosoma cruzi 1f29, 1f2a, 1f2b, 1f2c, 1ewo, 3lxs - Cru catalytic domain + vinyl sulfone derived inhibitor 1ewl, 1ewm – Cru catalytic domain + methylbutane inhibitor

spinqualitylabelsall models Structure of cruzain complex with methylketone inhibitor (PDB entry 1me3) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image