V-ATPase

Your Heading Here (maybe something like 'Structure')Your Heading Here (maybe something like 'Structure')

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spinqualitylabelsall models Fitted structure of Thermus thermophilus V-ATPase, based on the EMD-5335 (PDB entry 3j0j) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

IntroductionIntroduction

V-ATPase are mainly found in vacuoles of eukaryotic cells where they catalyze the hydrolyzation of ATP in order to transport solutes.

V-ATPase componentsV-ATPase components

The structure of the whole V-ATPase complex can be divided in two domains. The V1 domain, which consist of eight different sub-units (A-H) and is responsible for the hydrolyzation of ATP, and the intermembrane V0 domain consisting of six different sub-units (a-f) and which transports the protons.

V-ATPase structuresV-ATPase structures

PDBPDB

3j0j

3a5c

3k5b

1r5z

EMDBEMDB

5335