4f1s
Crystal structure of human PI3K-gamma in complex with a pyridyl-triazine-sulfonamide inhibitorCrystal structure of human PI3K-gamma in complex with a pyridyl-triazine-sulfonamide inhibitor
About this StructureAbout this Structure
4f1s is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Wurz RP, Liu L, Yang K, Nishimura N, Bo Y, Pettus LH, Caenepeel S, Freeman DJ, McCarter JD, Mullady EL, Miguel TS, Wang L, Zhang N, Andrews KL, Whittington DA, Jiang J, Subramanian R, Hughes PE, Norman MH. Synthesis and structure-activity relationships of dual PI3K/mTOR inhibitors based on a 4-amino-6-methyl-1,3,5-triazine sulfonamide scaffold. Bioorg Med Chem Lett. 2012 Jul 3. PMID:22832322 doi:10.1016/j.bmcl.2012.06.078