3tpp
Crystal structure of BACE1 complexed with an inhibitorCrystal structure of BACE1 complexed with an inhibitor
Template:ABSTRACT PUBMED 22194329
About this StructureAbout this Structure
3tpp is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
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ReferenceReference
- ↑ Xu Y, Li MJ, Greenblatt H, Chen W, Paz A, Dym O, Peleg Y, Chen T, Shen X, He J, Jiang H, Silman I, Sussman JL. Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations. Acta Crystallogr D Biol Crystallogr. 2012 Jan;68(Pt 1):13-25. Epub 2011 Dec 9. PMID:22194329 doi:10.1107/S0907444911047251