Proteopedia

2pf8

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Template:STRUCTURE 2pf8

File:2pf8.png

Complex of Aldose Reductase with NADP+ and simaltaneously bound competetive inhibitors Fidarestat and IDD594. Concentration of Fidarestat in soaking solution is equal to concentration of IDD594.Complex of Aldose Reductase with NADP+ and simaltaneously bound competetive inhibitors Fidarestat and IDD594. Concentration of Fidarestat in soaking solution is equal to concentration of IDD594.

Template:ABSTRACT PUBMED 22752989

About this StructureAbout this Structure

2pf8 is a 1 chain structure of Aldose Reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Cousido-Siah A, Petrova T, Hazemann I, Mitschler A, Ruiz FX, Howard E, Ginell S, Atmanene C, Van Dorsselaer A, Sanglier-Cianferani S, Joachimiak A, Podjarny A. Crystal packing modifies ligand binding affinity: The case of aldose reductase. Proteins. 2012 Jul 2. doi: 10.1002/prot.24136. PMID:22752989 doi:10.1002/prot.24136

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